Suprastin is classified as a first-generation antihistamine. Despite the fact that the pharmaceutical industry today presents many of its safer counterparts, it is still popular. Moreover, they use it in pediatrics, prescribing Suprastin to children to stop allergic manifestations and prevent their dangerous complications.

The composition and release forms of the drug for children

The active substance that provides the therapeutic effect of the drug is chloropyramine hydrochloride. Depending on the form of the product, various substances supplement it.

Suprastin tablets, in addition to the main component, contain:

  • stearic acid;
  • potato starch granules;
  • lactose monohydrate;
  • gelatin compounds;
  • carboxymethyl starch Na group A.

White or grayish tablets in the middle are divided by scoring, and there is also an engraving with an international name. They are sealed in blisters packed in cardboard packages. In one box they can be 1 or 2 pieces.

And also Suprastin is released as a solution for intramuscular administration. There is a basic substance and water for injection. It is an almost colorless liquid with a very subtle specific smell. It is poured into containers of tinted glass screwed with plastic caps. Ampoules are laid out in cardboard boxes of 20 pieces. Other forms of the drug do not exist.

The medical product retains its medicinal properties for 5 years that have passed since the release. It must be stored in a room with a temperature of 15 to 25 degrees, and protected from exposure to sunlight.

Attention! If the pharmaceutical composition in tablet form can be purchased at the pharmacy completely freely, then when buying Suprastin injections, you will need to present a doctor's prescription.

Pharmacological action, pharmacodynamics and pharmacokinetics

The therapeutic composition has a pronounced anti-allergic and antihistamine effect. And he is able to have an antiemetic and moderate antispasmodic effect.

After the drug enters the body, its absorption occurs rather quickly, it is rapidly distributed in the cells. Relief occurs after a quarter of an hour. The active substance is almost completely absorbed from the digestive tract, and reaches the maximum concentration in the blood after about 60 minutes. The effect of the application lasts from 3.5 to 6-7 hours.

The metabolism of chloropyramine hydrochloride is produced by the liver, and excretion is carried out by the kidneys. It is noteworthy that in the child’s body this process proceeds somewhat faster than in adults.

Why is Suprastin prescribed for children?

According to the instructions for use, Suprastin is allowed for a child to be prescribed for the following conditions:

  • allergies to food or medicine;
  • serum sickness;
  • rhinitis of an allergic nature;
  • conjunctivitis of different origin;
  • urticaria;
  • skin itch of any etiology;
  • dermatological problems;
  • acute and chronic eczema;
  • acute reaction to insect bites;
  • Quincke's edema.

On a note. This is an allergy medicine for children and is prescribed before a Mantoux test or Diaskintest test with high sensitivity to the components of the vaccine.

Instructions for use and dosage for the child

In each case, the doctor prescribes an individual dosage of the drug. In the annotation to a medical device, only common schemes for its use are described.

Suprastin Tablets

The daily volume of the drug composition is prescribed depending on the age of the patient. For infants, it will be a fourth or fifth of the pill twice a day.

Patients under 6 years of age are shown one tablet per day, which should be divided into two doses.

From 6 to 14 years old Suprastin drink 1-1.5 tablets two to three times a day. In this case, once you can take no more than 1/2 part.

Attention! The maximum daily dose for children is 2 mg of the drug per 1 kg of weight.

Solution in ampoules for injections

Suprastin solution is intended for injections intramuscularly, but in special cases it can be administered intravenously. As a rule, this is done in the initial stages of therapy.

The dosage for different age categories is as follows:

  • babies up to a year - 0.25 ml;
  • from 12 months to 6 years - 0.5 ml;
  • from 6 to 14 years old - 0.5-1 ml.

As with the use of the tablet form, the allowed volume of solution per day is no more than 2 mg per 1 kg of patient weight.

Attention! Suprastin in the form of tablets or injections is not prescribed for newborns.

Drug interaction

Chloropyramine hydrochloride is classified as potent compounds that can enter into pronounced chemical reactions with other components. Therefore, there are a number of restrictions for the combination of Suprastin with other medicines.

This medication enhances the effects of these groups of medicines:

  • analgesic formulations;
  • atropines;
  • sympatholytics;
  • tranquilizers;
  • MAO inhibitors;
  • sedatives.

When there is a need for joint therapy, it takes place only under strict medical supervision.

Contraindications, side effects and overdose

The main conditions for the appointment of Suprastin include the following conditions:

  • high susceptibility to the components of the drug;
  • imbalance of lactose in the body or its intolerance;
  • bronchial asthma during acute attacks;
  • age up to 3 years (for a tablet);
  • infant age (for all forms).

Caution is required if the patient has been diagnosed with the following conditions:

  • closed-angle glaucoma;
  • disorders in the liver and kidneys;
  • impaired functionality of the cardiovascular system;
  • urinary tract diseases.

Composition provokes side effects extremely rarely, often they disappear after its withdrawal.

Undesirable manifestations include:

  • urination disorders;
  • loss of vision;
  • decreased muscle tone;
  • diarrhea and constipation;
  • nausea and vomiting
  • impaired appetite;
  • cramps in the stomach;
  • pressure surges;
  • malfunctions in the heart rhythm;
  • increased intraocular pressure;
  • constant feeling of tiredness;
  • dizziness and trembling limbs;
  • headache;
  • convulsive manifestations;
  • changes in blood composition;
  • various allergic manifestations.

As a result of exceeding the recommended dosage, the following symptoms appear:

  • the child becomes restless, agitated and overly anxious;
  • impaired coordination of movements and perception, hallucinations are possible;
  • there is an expansion of the pupils, redness of the skin on the face;
  • the patient has a heartbeat, quite often there is a fever and convulsions;
  • frequent urination disorders;
  • in especially severe cases, a coma occurs.

In such situations, it is indicated to rinse the stomach, followed by intake of sorbents and symptomatic therapy.

Allergy drug analogues

Today, pharmacies have a lot of medicines that have properties similar to Suprastin. If the latter is contraindicated, it is replaced by Fenistil, Tavegil, Zirtek, Claritin, Diazolin or Diphenhydramine.

Since all these drugs differ in degree of effectiveness and are based on different substances, the choice of therapeutic composition remains with the specialist. The unauthorized appointment of a medication can lead to dangerous consequences.

Similar:More from the author: