A runny nose does not always go away on its own or is corrected by standard vasoconstrictive drops. Sometimes it is allergic in nature, so conventional therapeutic regimens do not work. Then Nazonex comes to the rescue.

Nasonex Nasal Spray Composition

Nasonex contains a component related to glucocorticosteroids (GCS) - mometasone furoate. Its volume in one press of the spray is 50 mcg. This is taken into account when choosing a treatment regimen.

As additional components in the drops are present: water, dispersed cellulose, polysorbate 80, sodium citrate in the form of dihydrate, benzalkonium chloride, glycerol and phenylethyl alcohol. These substances allow mometasone to remain active, and also provide a convenient dosage form. The drug is made in the form of a white suspension. In a bottle of thin plastic it contains 120 clicks.

Pharmacological properties and indications for use

Nasonex spray has two effects at once - it relieves inflammation and reduces the intensity of allergic manifestations. The result is achieved by suppressing the synthesis of specialized mediators, including arachidonic acid and its derivatives. The drug affects the migration of macrophages, and also prevents the accumulation of neutrophils.As a result, swelling is relieved, nasal breathing improves, and the amount of exudate secreted decreases.

The elimination of allergic manifestations extends to both a delayed and an immediate type of reaction. This ensures maximum effectiveness of the drug. An anti-inflammatory effect on the membrane of the upper respiratory tract develops at any stage of the disease, which allows the use of Nazonex nasal spray even in advanced cases.

The active substance of the drops does not enter the blood, therefore it is allowed to use Nasonex for children.

The medicine is effective in several conditions:

  • acute sinusitis in patients from 12 years old;
  • allergic rhinitis in patients from 2 years;
  • high risk of exacerbation of chronic rhinitis due to allergies.

Prevention with the drug begins 2-4 weeks before the start of the allergy season. It usually runs from the end of spring and throughout the summer.

Important! Long-term use of Nasonex is not addictive, therefore it is allowed to repeat the course annually.

At what age can children use

Nasonex is a high activity drug. Therefore, its use is possible in children from 2 years old. Up to this age, it is recommended to use analogues with a lower dosage.

Instructions for use and dosage regimen spray Nazonex

The drug is administered intranasally. The nebulizer allows the solution to penetrate deeper into the respiratory passages. The dose is determined by the number of clicks on the bottle.

Before starting treatment, you need to press the bottle 6-7 times so that the air leaves the tube and the medicine enters the dispenser. One injection of the drug is equal to 50 μg of mometasone furoate. If not used for 2 weeks, the spray preparation procedure must be repeated. Each time before entering Nazonex, it is worth shaking the packaging with the solution several times.

Therapy for more than 12 months does not adversely affect the mucous membrane of the nasal passages. At the tissue level, an improvement was noted in the form of the disappearance of signs of an allergic reaction. This increases local immunity and contributes to a more rare occurrence of seizures.

For children

Instructions for use allow the appointment of the drug from 2 years of age. Up to 11 years, it is worth using the spray 1 time per day for 1 click in the nostril. In just a day, the child receives 100 micrograms of the active ingredient. After reaching 12 years, children are equated with adults and treated according to their scheme.

For adults

In the presence of allergic rhinitis, the Nazonex nasal spray is used as monotherapy for 2 clicks in 1 nostril once a day. In total, the patient receives 100 mcg of the drug. With positive dynamics from therapy, the dosage can be reduced to a single injection of 1 spray in each respiratory passage per day.

If there is no noticeable therapeutic effect, the dosage is doubled (4 times a day, one nostril once per day). With persistent improvement, the amount of the drug is gradually reduced.

Important! The first signs of the action of the drug are noted on the day of use.

As part of the complex treatment of sinusitis, Nazonex is prescribed to the nose in adults in the amount of 2 injections in each nasal opening twice a day. The volume of the drug can be increased by 2 times in the absence of a noticeable effect of treatment. With a decrease in symptoms, the dosage is gradually reduced.

Pregnancy and lactation

When using the medicine for its intended purpose, it is not found in the blood. Therefore, it can be considered safe in relation to women carrying and nursing children. But due to the lack of experimental studies in these categories of people, Nazonex should be prescribed only in case of urgent need. After the birth of the child, the mother receiving such treatment needs to examine the functional state of the adrenal glands of the baby.

Drug Interactions with Other Drugs

In laboratory conditions, the interaction with loratadine was studied. Combined treatment with these drugs gave a better effect compared to monotherapy. Nasonex does not have a pronounced effect on other drugs. The active substance does not enter the blood, therefore the systemic effect is weak and is not taken into account when selecting therapeutic combinations of drugs.

Contraindications, side effects and overdose

Drugs from the group of glucocorticosteroids have a significant effect on the body with both systemic and local application.

Therefore, they have contraindications for use:

  • active infectious process in the nasal cavity;
  • hypersensitivity to substances in the composition of the drug;
  • pulmonary tuberculosis of any form;
  • fresh injury to the tissues of the nose;
  • systemic viral or bacterial infection;
  • recent surgery on the nose;
  • herpetic damage to the eyes;
  • patient age up to 2 years.

Important! In some cases, the use of the drug is permissible even if there are contraindications. In this case, an individual dosage and treatment regimen are selected.

If the rules for using the medicine are not observed, side effects may occur.

They are expressed in several manifestations:

  • burning sensation at the place of use;
  • nosebleeds;
  • irritation of the nasal mucosa, expressed by sneezing;
  • pharyngitis;
  • headache.

In rare cases, when using the drug, intraocular pressure may increase and the nasal septum is perforated. These conditions require immediate withdrawal of the medicine and seek medical attention. Treatment of side effects consists of symptomatic therapy and the selection of an analogue of Nazonex.

Exceeding the recommended dosage is accompanied by characteristic symptoms. For glucocorticosteroids, this is a decrease in the activity of the adrenal system, hypothalamus and pituitary gland. The condition is characterized by serious hormonal disorders and a significant deterioration in the patient's well-being. To restore the body, drug withdrawal and symptomatic therapy are required.

Analogs of nasal spray

Due to the high cost of the drug, patients can look for analogues cheaper than Nazonex. The most popular of them is Desrinitis. Its cost is two times lower, and the active substance is identical to the original. You can also replace it with Asmanex Twistheiler and Rizonel. But the effectiveness of generics may vary due to the nature of production, the quality of raw materials and additional ingredients. Therefore, to select the right dosage, you should consult a specialist.

An analogue to the effect on the nasal mucosa can be considered the drug Polydex. It also contains glucocorticoid (dexamethasone), which relieves edema and inflammation. The medicine has several active substances at once - it contains neomycin sulfate, phenylephrine hydrochloride and polymyxin. Therefore, its effect is stronger than that of Nazonex, and the list of side effects and contraindications has been expanded. It is not worth it to replace these funds with each other on their own.

Beconase also refers to steroid medications for the common cold. It contains beclomethasone in a dosage of 50 mg. This medicine is produced in Spain, so its cost is different from Nazonex. According to the mechanism of action, the agents are completely identical, but due to differences in composition, it is worth visiting a specialist before replacing one with another.

Several drugs with other active ingredients have a similar effect to nasonex.

These include:

  • Aldecin;
  • Flutinex;
  • Benacap;
  • Fluticasone;
  • Avamis;
  • Benarin;
  • Flixonase;
  • Budoster;
  • Beclomethasone;
  • Tafen;
  • Insect;
  • Binocularyl;
  • Nazarel.

Dosages and characteristics of analogues may differ significantly from the original drug. Self-replacement of one drug with another can lead to loss of treatment effectiveness and deterioration of the patient's condition.Therefore, this decision cannot be made independently and requires consultation with a doctor.

Nasonex is considered the most effective drug for allergic rhinitis and sinusitis. Its use helps to quickly improve the patient's condition, as well as to prevent the recurrence of attacks. The medicine can be replaced by an analog, but with a mandatory dosage adjustment. This will help to avoid side effects and possible complications.

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