The appointment of "Monural" during pregnancy is not always associated with a serious illness. The drug can be taken as a preventive measure. After all, a random infection can pass from mother to fetus, and this can not be allowed in any case.
Material Content:
The composition of the drug
Antibiotic Monural contains 2 - 3 g of fosfomycin in 1 sachet. Sugars and citrus flavors are used as additional components. The drug is available in the form of granules for dissolution in water and ingestion. Each dose is in an individual package of paper coated with polyethylene. In a box of thin cardboard lies 1 - 2 bags.
The medicine stops the first stage of the formation of the cytoplasmic membrane, due to which the pathogen is destroyed. "Monural" affects many bacteria sensitive to it.
These include:
- enterococci;
- staphylococci;
- Escherichia;
- enterobacteria;
- morganella;
- cytobacteria;
- Klebsiella;
- Proteus
- serrates;
- pseudomonads.
In some microorganisms, Monural reduces the ability to fix on the epithelium of the urinary organs.
The maximum amount of the drug is observed after 2 - 2.5 hours after administration. It is well absorbed by oral administration. The active substance accumulates in the urine.
The concentration of the active substance is maintained at a high level from 24 to 48 hours. Therefore, the entire course of treatment is taking 1 sachet.
Why is Monural prescribed during planning and during pregnancy?
Instructions for use of the drug contain a large list of prescriptions.
It includes:
- urethral inflammation;
- acute bacterial cystitis or chronic relapse;
- urethral syndrome;
- massive volume bacteriuria in pregnant women without symptoms;
- prevention of urinary tract diseases when performing diagnostic measures through the urethra.
Treatment with Monural before pregnancy will help to prevent the infection from passing from the urinary tract to the genitals of a woman. During the bearing of the child, the drug can be prescribed if a large number of bacteria in the urine are detected without other signs of inflammation. This helps prevent the development of renal pathology, which can harm both the expectant mother and her baby.
Instructions for the use of powder at different times
The drug is always taken orally on an empty stomach, before meals for 2 hours or after it. It is recommended to do this in the evening before going to bed. First, you should visit the restroom and empty the contents of the bladder.
- Prescribe "Monural" during pregnancy in the early stages may be due to the detection of a high concentration of bacteria in the urine. The dosage of the drug is 1 sachet of 3 g, diluted 1/3 tbsp. pure water. The drug is taken once.
- In the 2nd trimester, you can take Monural 2 days in a row. This treatment regimen is selected in the presence of a relapse of diseases of the genitourinary system. For a day you need to take 1 sachet with 3 g of the active component.
- With kidney failure, the dosage is reduced to comfortable values. This condition can develop in the third trimester due to the increased load on the internal organs.
- Women with diabetes or gestational diabetes should also be cautious, since the composition of the drug contains 2.1 g of sucrose in a 2 g sachet and 2.2 g in a package of 3 g of the active component.
Drug interaction
"Monural" is able to mutually enhance the action of cephalexin, amoxicillin and pipemidic acid. This should be taken into account with complex treatment with drugs.
But the combination with metoclopramide should be excluded. It reduces the effectiveness of uroantiseptic. For a pronounced effect, its dosage will have to be increased, which can cause undesirable phenomena in the form of disorders of the digestive tract.
How an antibiotic affects the fetus
The drug practically does not enter the bloodstream. The active substance is collected in the kidneys, from where it then leaves the urine unchanged. For this reason, Monural does not affect the fetus, so it is allowed to use it at any stage of pregnancy.
Contraindications, side effects and overdose
Since the medicine does not have a systemic effect, he does not have many contraindications. These include only a severe degree of renal failure, hyperreactivity to the components of the drug and age in children under 5 years old. The last limitation is associated with the risk of toxic effects on the urinary organs due to the high concentration.
Among the side effects are local reactions of the organs of the gastrointestinal tract (diarrhea, heartburn, nausea) and allergic manifestations (rashes). There were no specific signs of an overdose, but if you accidentally swallow a large amount of the drug, you should wash the stomach and take enterosorbent.
Analogues of Monural
Phosphoral Rompharm is a fast-acting medicine for cystitis and other pathologies of the excretory system. It is available in the form of granules packed in individual bags of 3 g of active substance. As an active ingredient, fosfomycin was used. Indications for use in the medicine are similar to those of Monural, since they have almost the same composition. The difference is the absence of calcium hydroxide in the original product, which makes it more hypoallergenic.
In the form of granules for dissolution in water and subsequent use, Ecofomural is also orally produced.The proportion of active substance in it is also 3 g, and the drug is packaged in individual bags. As a second active component, the agent contains lactulose. It has a prebiotic effect on the intestines, helping to quickly return the microflora to normal. But when appointing, you need to consider that lactulose is not suitable for all patients. For some, its presence in the composition will be a contraindication to use.
Of the Russian counterparts, one can distinguish "Uronormin - F". It is made in the form of a powder that dissolves in water. The resulting solution is taken orally.
The drug has several forms of release:
- 2 g of active substance, 1 pc. packaged,
- 3 g put 1 or 2 sachets.
The active ingredient in the composition is also fosfomycin.
The pharmacological effect of the drug is similar to the original drug. This is due to the almost complete identity of their compositions. The medicine is also collected in the urine, where it acts as a bacteriostatic. Uronormin-F can be used during pregnancy, since it practically does not penetrate the blood.
Analogues of "Monural" have the same active substance as the original drug. But besides this, other components are added to them. This increases the risk of allergic reactions, since it is the lower, the less substances in the composition of the product.
"Monural" is considered a well-known and effective drug for inflammatory diseases of the excretory system caused by infection. It is used both for treatment and for the prevention of pathological conditions. The medicine is safe for pregnant women, since it does not have a systemic effect. It can be used at any time, which makes the drug a universal assistant for expectant mothers.
