Clotrimazole cream is a drug for external use in the treatment of skin diseases caused by pathogens, pathogenic fungi. It is an easily absorbable, white, odorless mass produced in tubes of 200 g.
Material Content:
Description of the dosage form, composition
Clotrimazole is an antifungal agent that has the ability to destroy the integrity of the cell membrane of microorganisms, causing their death.
Clotrimazole vaginal cream 2% contains in 100 g of the total mass 2 g of the active ingredient, concomitant and filling ingredients, 1% clotrimazole cream contains 1 g of the active substance.
The drug suppresses vital activity:
- pathogenic fungi;
- protozoa, pathogens, giving a positive Gram stain test, and anaerobic microorganisms.
The drug enters the bloodstream in the amount of 3 - 10% of the total amount of the used drug, while maintaining the ability to suppress the vital activity of pathogenic cultures, for 2 to 3 days, then it breaks down into simple components and is excreted from the body.
Why is Clotrimazole prescribed?
Clotrimazole helps with fungal diseases of the skin and mucous membranes caused by infection and vital activity in seeded areas by pathogens, pathogenic fungi:
- multicolored lichen, erythrasma;
- genital infections caused by Candida fungi: candida vulvovaginitis, trichomoniasis;
- mycoses, in a complicated form, secondary pyoderma;
- thrush.
Cream Instructions
Instructions for use contain instructions for preparatory procedures, treatment rules:
- before applying the cream, it is necessary to wash the affected areas of the skin, or intimate places with a detergent, preferably baby soap, since a high concentration of alkali in an antibacterial safe guard or laundry soap leaves an alkaline reaction in the form of a protective layer on the seeded surface of the skin and mucous membrane, weakening the aggressive ability of the drug in relation to pathogens;
- the cream is applied by rubbing with gentle pressure on infected, pre-treated areas, from 2 to 3 times during the day (depending on the spread and severity of the infection), capturing the adjacent areas, to eliminate the possible spread of microorganisms to healthy areas of the body;
- on the nail plate, the cream is applied after baths with potassium permanganate, capturing the area around the nail, you can apply the cream in a thick layer and leave the application for a day, applying a bandage and fixing it with a bactericidal patch;
- in the treatment of foot fungus and in the area between the fingers after applying the cream, put on clean cotton socks;
- the full course of treatment is 4 weeks, improvements occur during the first week of the procedure;
- since pathogenic organisms have a high degree of reproducibility and vitality, and intimate places represent a beneficial environment, one spore of a fungus or microorganism cell is necessary for their further development and vital activity, which will lead to the resumption of the disease;
- at the end of treatment and in the absence of irritating symptoms, it is necessary to continue the procedure for the next 2 weeks for the purpose of prevention;
- for genital infections, before dosing, it is necessary to douche using mild disinfectants or a weak solution of clotrimazole, after which the vaginal cream, applied in an amount of 5 g on a sterile swab, is introduced into the vagina, leaving it for 24 hours, the procedure is repeated 3 times;
- at the same time, the external genitalia are treated with a cream to prevent the spread of infection;
- after removing the swab, douching is performed.
The treatment procedures are not performed during the period of menstruation, it is necessary to wait 2 to 3 days after the termination of the cycle.
During treatment, sexual contact is undesirable, otherwise it is necessary to use reliable personal protective equipment.
When resuming signs of the disease, it is necessary to conduct a second examination in order to clarify the reliability of the correct diagnosis and consult a doctor for new appointments.
To exclude the resumption of the disease, it is necessary to observe the rules of personal hygiene.
During pregnancy and lactation
During pregnancy, during treatment, the cream is injected directly into the vagina without the use of a tampon.
Treatment of sexual infection in the first trimester of pregnancy with clotrimazole is contraindicated, the possibility of treatment in the rest of the pregnancy is decided by the attending physician.
If it is necessary to treat the infection in a nursing mother, the infant must, temporarily, be transferred to artificial feeding.
Drug interaction
Clotrimazole reduces the effectiveness of taking a number of antibiotics.
When combined with nystatin, the effect of the drugs is neutralized, the therapeutic effect is reduced.
The simultaneous ingestion of drugs: tacrolimus or sirolimus contributes to the accumulation of the concentration of the latter in the blood, which can cause an overdose and negative side effects, therefore, analytical control with the performance of a blood test is necessary.
Contraindications, side effects and overdose
Contraindications for treatment with Clotrimazole are individual intolerance, local allergic reactions in the form of itching, redness, and the first trimester of pregnancy.
Before use, it is necessary to check the tolerance of the use of the drug by the body, spreading a thin layer of cream on a sensitive area of the skin (wrist or ulnar bend) and withstand 30 minutes, in case of redness, irritation, the drug must be replaced with another analog.
The side effects of the cream were identified:
- urticaria, low blood pressure, loss of consciousness;
- pain in the abdomen;
- frequent urination, inflammation of the urinary system;
- migraine, stomach dysfunction;
- itching, burning, swelling of the genital organs.
The fact of the use of the cream on the ability to drive vehicles, perform work at heights, and other types of hazardous work has not been established.
With individual tolerance of the drug, treatment can last a long period of up to 2 months, in case of signs of deterioration and side effects, it is necessary to consult a doctor.
Analogues of the drug
Among antifungal drugs, there is a wide variety of analogues and generics (they have the identical composition, but are available without a patent and license, inexpensive).
Antifungal analogues:
Pimafucin, Nystatin Ointment, Ketozoral, Miconazole, Dactanol, Ketoconazole.
Generics: Kanizon, Kanesten, Candide, Imidil, Candibene, Antifungol, Funginal, Faktodin, Lotrimin, Amiklon.
Compliance with personal hygiene, the right way of life, the constancy of sexual partners - are a guarantee of health.
