Prevention of thrombosis and atherosclerosis, support of cardiac activity are just some of the properties of this popular medicine. Before taking Cardiomagnyl, patients try to find out about its pros and cons. This is a combination drug, an improved version of cardioaspirin.
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Indications Cardiomagnyl
Acetylsalicylic acid (ASA) is a non-steroidal anti-inflammatory drug that exhibits typical NSAIDs. Cardioaspirin is considered ASA in low doses. The medication has a therapeutic effect that is beneficial for the heart and blood vessels, for example, prevent the formation of blood clots.
Aspirin causes an increase in the activity of secretory cells in the walls of the stomach.
Cardiomagnyl is a successful combination of cardioaspirin and magnesium. Dosages of active substances in tablets: 75 + 15.2 mg, 150 + 30.4 mg. The second active component is included to protect the gastrointestinal mucosa. Magnesium hydroxide neutralizes excess hydrochloric acid. This helps to prevent the negative effects of treatment on the digestive tract.
In which pathological conditions do they take the drug:
- a high probability of developing repeated myocardial infarction;
- coronary heart disease (CHD);
- primary and secondary thrombosis;
- heart failure;
- unstable angina pectoris;
- risk of thromboembolism;
- the dangers of stroke;
- atherosclerosis.
The drug is often prescribed to patients after 60 years with high blood pressure, hyperlipidemia, a predisposition to cardiovascular disease.Cardiomagnyl is used as an antiplatelet agent for chronic venous circulation failure. ASA inhibits the activity of an enzyme that causes platelet accumulation and clot formation in blood vessels.
How to take the drug for treatment
A maintenance daily dose of 75 mg is recommended for most diseases and conditions listed in the list of indications. The same dosage is observed if Cardiomagnyl is prescribed to thin the blood. Such an action is useful, for example, with a risk of thromboembolism, varicose veins. When diagnosed with unstable angina, 75 or 150 are prescribed, chronic ischemia - 150 mg / day.
What time of day
There is a version that taking Cardiomagnyl in the evening improves falling asleep. You can take the pill after dinner. It is useful for arterial hypertension. However, heavy food, coupled with a decrease in metabolic activity of the body at night, slows down absorption. Therefore, taking Cardiomagnyl in the morning has several advantages.
Before or after a meal
The fear that ASA without a membrane irritates the gastric mucosa is not entirely objective. Aspirin is rapidly adsorbed, enters the bloodstream and then acts on the glands that produce hydrochloric acid. Therefore, it does not matter in what form the medicine will enter the stomach.
Almost all NSAIDs are recommended to be drunk only after a meal, since drugs of this group negatively affect the gastrointestinal tract.
Some patients experience discomfort by swallowing a hard pill. It is allowed to break, chew. The medicine should be washed down with ½ cup of water. You can crush the tablet, dissolve the powder in 1 tbsp. l water.
A course of treatment
The doctor determines the total duration of the use of the drug individually, taking into account the age, diagnosis, presence of excess weight in the patient. If the condition or disease is not started, then the course of treatment can be 1 month. The drug for hypertension should be drunk for 2-3 months.
The answer to the question of how long you can take Cardiomagnyl without a break also depends on a number of factors. Usually the course lasts no more than 5 months and up to six months. Experts recommend taking breaks, for example, not taking the medicine for 2-4 weeks after a month of therapy.
Admission Rules for Disease Prevention
If the drug is prescribed to prevent primary or secondary thrombosis, then at first the dosage is 150 mg / day. With a reduced risk of complications, the daily dose is reduced by 2 times.
Cardiomagnyl administration for prophylaxis:
- acute heart failure - 150 on the first day, then 75 mg each;
- thromboembolism after vascular surgery - 75-150 mg;
- Reinfarction - from 75 to 150 mg.
Elevated doses of the substance are required for patients with diagnosed obesity. If the body mass index is more than 40, then take from 150 to 200 mg.
During pregnancy and lactation
Safe is considered a daily dose of 150 mg of ASA and below. This is category A in the international classification (low probability of harmful effects). The risk for an unborn child is the amount of ASA 500 mg and above, which belongs to category D.
The combination of ASA + magnesium has a teratogenic effect. In the first three months after conception, taking the medicine increases the likelihood of a defect in the fetus, in the last three months it slows down labor and can cause bleeding.
Cardiomagnyl in the 1st and 3rd trimesters is not prescribed.
From 4 to 6 months of pregnancy, taking cardioaspirin and other salicylates is possible only according to strict indications. The doctor must weigh the pros and cons, determine whether the therapy will bring undoubted benefits to the mother's body, and whether irreparable damage to the health of the unborn child will be inflicted.
Before prescribing Cardiomagnyl during lactation, the doctor assesses the potential benefits of treatment for a nursing woman regarding the possible harm to the baby. Usually, mothers are advised to interrupt breastfeeding for the entire period of treatment with medications.
What contraindications exist
Particular attention should be paid to prohibitions and cautions relating to ASA. Cardiomagnyl intake is excluded for individuals with hemorrhagic diathesis, thrombocytopenia, and vitamin K deficiency. In these conditions, the tendency to bleeding increases.
The list of contraindications also includes:
- intolerance to the active and auxiliary ingredients of the drug;
- "Aspirin" asthma that arose on the background of taking salicylates and NSAIDs;
- exacerbation of erosive lesions, relapse of an ulcer, bleeding in the digestive tract;
- concurrent treatment with methotrexate;
- impaired liver function;
- age to 18 years.
With hyperuricemia, gout, allergic conditions, nasal polyps, the drug is prescribed with caution. Cardioaspirin is able to aggravate the course of certain diseases.
Side effects and overdose
Cardiomagnyl treatment may be accompanied by the development of an allergic reaction. Symptoms of this condition are very diverse. Most often, the following symptoms appear: runny nose, redness and itching of the skin, rash in the form of nodules or blisters. In some cases, Cardiomagnyl causes angioedema, bronchospasm.
List of other possible side effects of various organ systems:
- Reflux esophagitis, pain in the epigastric region, vomiting, dyspepsia, problems with stool, erosive phenomena, ulcerative colitis, hepatitis.
- Increased risk of nosebleeds, thrombocytopenia, agranulocytosis.
- Headaches, drowsiness, less commonly cerebral hemorrhage.
- Tinnitus, reversible deafness and loss of coordination.
Dutch researchers have relatively recently found that patients over 60 years old should beware of large doses of cardioaspirin. Such therapy increases the risk of vision loss by 2 times. And also taking ASA daily for a long period of time is a possible cause of cerebral hemorrhage. The risk of bleeding, including in the digestive tract, is about 1.2–1.5%.
Elderly people take Cardiomagnyl for a long time, despite the existing risk of treatment with cardioaspirin. Experts have recognized that for the body with heart disease, the drug has more benefits than harm.
The safe dose is 150 mg, the maximum is not more than 4 g / day.
High single and daily dosages are dangerous. The first symptoms of adverse manifestations are nausea, excessive sweating, ringing in the ears, deafness, and swelling. With moderate symptoms of exceeding the amount of taken funds, it is enough to take an enterosorbent, for example, activated carbon. Symptomatic remedies are used. A patient with signs of acute severe intoxication of ASA needs emergency medical care.
Cardiomagnyl is intended for the prevention of strokes, repeated heart attacks in patients at risk of developing these conditions. The drug is prescribed for complications of atherosclerosis, other pathologies of the heart and blood vessels.
