To carry a child, a woman's body expends a large amount of strength and resources. This can trigger an exacerbation of chronic diseases and create a critical situation. In this case, the appointment of Eufillin during pregnancy is justified to save the lives of the mother and fetus.

Is it possible to take Eufillin at 1, 2, 3 trimesters

The appointment of Eufillin when carrying a child is possible at any time. In the early stages, it is more often used by women with pathologies of the respiratory tract. In later ones, it is used for edema during pregnancy, associated with an increased burden on the kidneys.

Description of release forms and composition

Eufillin tablets contain 150 mg of aminophylline. They are packed in boxes of thin cardboard with 3 blisters, each of which contains 10 pcs. The active ingredient acts as a diuretic, antispasmodic and bronchodilator.

The drug also exists as a yellowish or clear injection. 1 ml contains 24 mg of the active ingredient, as well as specially purified water. Inside the ampoule may be 5 or 10 ml of the product. They are placed in packages of 10-20 pcs. For convenience, a scarifier or an ampoule knife for opening is enclosed in the box, as well as instructions for use in printed form.

The medicine acts on smooth muscle cells, relaxing them. It is able to relieve bronchospasm due to its action as an inhibitor of phosphodiesterase and a decrease in the concentration of calcium ions in the blood.The provided effect increases mucociliary clearance and improves the work of the auxiliary respiratory muscles. At the same time, the activity of the center of inspiration in the cerebral cortex increases and ventilation in the alveoli increases. Thus, breathing becomes even, and oxygen concentration in the blood rises.

Eufillin has an exciting effect on the heart, accelerating its work and increasing the force of contractions. As a result, his muscles consume oxygen. In this case, the tone of the vessels decreases, and they expand, which reduces pressure. The blood flow to the organs of the excretory system rises, a small diuretic effect occurs.

The medicine is absorbed by 90-100%. The expansion of the bronchi is provoked with the amount of the drug from 10 to 20 μg / ml. Above this concentration, a toxic effect appears. Activation of the respiratory center occurs when in the blood from 5 to 10 μg / ml.

What is prescribed during pregnancy?

During the bearing of a child, chronic diseases often worsen in women. Pregnant women in the 1st trimester of Eufillin are prescribed for asthmatic status and bronchospasm.

Interesting! In the later stages, the drug is effective against edema of renal etiology.

They are rarely associated with diseases of the excretory system, and are more often caused due to the position of the child inside the mother. The use of Eufillin helps to avoid the development of preeclampsia and eclampsia or relieve their symptoms.

Instructions for use of tablets and solution

The tablets are intended for oral use. The dosage is 1 pc. 3-4 times a day. If the effect is needed immediately, the drug is injected into a vein at a slow pace for 4-6 minutes in an amount of 5 to 10 ml of liquid diluted in 10-20 ml of an isotonic solution.

If the patient is in asthmatic status, she is prescribed droppers with Eufillin in an amount of 720 to 750 mg. In this case, only a heated solution and not more than 250 mg at a time, and up to 500 mg per day can be administered intravenously. For children, the maximum dosage is determined based on weight: 3 mg per kg at a time. And per day - depending on age: up to 3 months from 30 to 60 mg, in 4-12 months from 60 to 90 mg, in 2-3 years from 90 to 120 mg, in 4-7 years from 120 to 240 mg, and from 8 to 18 years old from 250 to 500 mg. These concentrations are considered safe and do not provoke the development of side effects in the absence of individual intolerance.

The effect of the drug on the fetus

The drug penetrates 10% through the placenta. But it does not have a significant effect on the child. After birth, an increased concentration of the drug in the blood may be detected, but no negative effects have been noticed.

Drug interaction

Since Eufillin acts systemically, it is able to interact with other drugs.

When prescribing complex therapy, it is worth considering:

  • incompatibility with acid-based drugs;
  • increased chance of developing unpleasant symptoms while taking drugs for anesthesia (ventricular type arrhythmias), glucocorticoids, neurostimulants (increased toxicity to the nervous system), myocardiostimulants (increased sodium concentration in the blood);
  • increased potency due to combination with ticlopidine, macrolides, mexiletine, fluoroquinolones, lincomycin, enoxacin, verapamil, allopurinol, propafenone, cimetidine, ethanol, thiabendazole, isoprenaline, recombinant α-interferon, methotrexatom, disulfir;
  • increased withdrawal rate when interacting with phenobarbital, morazizin, carbamazepine, rifampicin, oral contraceptives with estrogens, isoniazid, aminoglutethimide, phenytoin and sulfinpyrazone;
  • a ban on the simultaneous use of xanthine with drugs;
  • increased effect of diuretics and β-adrenergic agonists;
  • deterioration in the activity of lithium-containing agents and β-adrenolytics.

With other antispasmodic drugs, the medicine is allowed to be used.Under the supervision of a specialist, it is possible to use anticoagulants together with Eufillin due to its antiplatelet properties. It is recommended to refuse or reduce the amount of food and drinks with a high concentration of caffeine in the composition. For older patients, the amount of medication can be reduced, and for smokers, patients can increase it, since they have it eliminated much faster.

Contraindications and side effects

Eufillin has a powerful effect on the body. In some cases, its use is unacceptable.

These situations include:

  • allergy to the components of the drug;
  • hyperreactivity to xanthine preparations (theobromine, caffeine and pentoxifylline);
  • low or high blood pressure;
  • breastfeeding time;
  • paroxysmal type tachycardia;
  • recent bleeding;
  • heart muscle infarction, accompanied by arrhythmia;
  • hemorrhagic type of stroke;
  • extrasystoles;
  • retinal hemorrhage;
  • epileptic seizures;
  • severe disruption of the liver or kidneys;
  • increased convulsive activity;
  • heart failure of a severe coronary type;
  • hypertrophic cardiomyopathy of an obstructive type;
  • pulmonary edema;
  • thyrotoxicosis.

The use of the drug in the presence of one of the deviations is impossible. In some cases, patients without contraindications experience side effects.

These include several conditions:

  • compaction at the injection site;
  • dizziness;
  • pain in the chest or head;
  • redness of the skin;
  • rashes;
  • sleep disturbances;
  • soreness localized at the puncture site;
  • itching
  • increased irritability;
  • rapid breathing;
  • arrhythmias of a different nature;
  • tremor of limbs;
  • increased sweating;
  • increase in body temperature;
  • pathological anxiety;
  • increased urine output;
  • increased angina pectoris;
  • pathological irritability;
  • low blood glucose
  • feeling of palpitations;
  • the appearance in the urine of red blood cells and protein;
  • tachycardia (may occur in a child in the treatment of a pregnant mother in the later stages;
  • feeling of hot flashes;
  • hypotension.

The severity of unpleasant symptoms increases in direct proportion to the amount of the drug taken. To get rid of side effects, it is shown to reduce the dosage. In some cases, the doctor selects a similar drug for replacement.

Analogs of a bronchodilator drug

In pharmacies, there are a lot of drugs with bronchodilating effect.

Analogues of Eufillin can be called several of them:

  1. Teotard capsules - are produced in Slovenia, contain 200 or 350 mg of theophylline in 1 pc., And 40 capsules are in the package. For pregnant women, the medicine is used under the supervision of a doctor and in the presence of weighty evidence.
  2. Combipek tablets are produced by a Russian company. The composition contains 6, 8 or 10 mg of salbutamol, which has a bronchodilator effect, and 200 mg of theophylline. The package contains 50 pcs. In pregnant women, the drug is not used.
  3. Aerodol Berodual N - contains ipratropium bromide 20 mcg and phenoterol hydrobromide 50 mcg in 1 injection. The volume of the vial is 10 ml.

Replacing Eufillin with an analogue can only be done with the permission of the attending physician. This is due to possible complications for the fetus and a ban on use in women during pregnancy. Since the original tool is also used to relieve edema in the later stages, a full replacement for the drug does not exist and is selected individually, based on the needs of the patient.

Eufillin has several effects that can alleviate the condition of a pregnant woman. Its safety level is sufficient so as not to worry about the condition of the fetus. But appointing it yourself is not recommended because of the risk of side effects.

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