To maintain the health and normal functioning of the cardiovascular system, specialists often prescribe enalapril. However, for some reasons, it is not always possible to use this antihypertensive medication. A number of pharmaceutical companies produce enalapril analogs that contain an identical active compound.

The composition of the drug for the treatment of hypertension

The central active compound is enalapril, an ACE inhibitor (5, 10 or 20 mg). Also, in the component composition there are a number of additional compounds: crospovidone, stearate and magnesium carbonate, gelatin, lactose monohydrate, corn starch, magnesium salt, silicon dioxide, dyes. The active compound of the drug is often involved in cardiology for the treatment of hypertension.

Russian analogues of enalapril

To replace the prescribed medication, you can pay attention to synonymous drugs that are produced by Russian pharmaceutical companies. These drugs belong to the new generation of inhibitors, have a minimum number of contraindications and rarely cause unwanted reactions in patients. The list of analogues that contain an identical active composition includes the following:

  1. Ramipril is often used in cardiology and neurology to prevent the development of signs of arterial hypertension, as well as the occurrence of myocardial infarction.
  2. Fosinopril is in demand for complex therapy with signs of heart failure and secondary hypertension.
  3. Captopril is a universal drug whose pharmacological properties are aimed at lowering blood pressure and preventing the development of diabetes mellitus.
  4. Lisinopril is an inhibitor that is advisable to use in various forms of arterial hypertension.
  5. Amlodipine - has a long hypotensive effect.

Before using Enalapril substitutes, it is recommended that you carefully read the contraindications and reception features.

Foreign drug substitutes

Foreign pharmaceutical companies produce drugs that contain a similar component composition, and are also able to have an identical pharmacological effect. The following inhibitors are synonymous with medications:

  • Enap (Slovenia);
  • Cardosal (Germany);
  • Aliskiren (Switzerland);
  • Rasilez (Switzerland);
  • Trifas (Germany)
  • Enalapril Hexal (Germany).

The listed medications belong to the middle price category and are somewhat cheaper than the original drug. These drugs are presented as tablets that do not cause coughing and a number of other side effects. The question of replacing the prescribed drug must be discussed with your doctor. Unauthorized appointment and uncontrolled reception can significantly worsen well-being and lead to complications.

Instructions for use and dosage

Prescribe this medication can only be a doctor who is familiar with the patient’s history. And also the specialist determines the optimal treatment regimen and recommended dosage. According to the instructions for use, enalapril must be used according to the following dosage rules:

  1. The standard amount of the drug is one tablet per day.
  2. It is recommended to use a therapeutic agent in the first half of the day (ideally up to 12 hours), since the tablets have diuretic properties.
  3. The initial amount of drug for experimental therapy is 5 mg. If no changes are observed, after two weeks the dosage is doubled.
  4. For therapeutic treatment of mild hypertension, 10 mg is indicated. The maximum allowable amount of the drug is 40 mg, which is divided into several doses.
  5. With drug treatment of high blood pressure or SS failure, the initial dosage is 2.5 mg. After a few days, the amount of the drug doubles.

Elderly patients are advised to take 1.25 mg. This remedy is used both before meals and after. The pharmacological properties of the drug appear half an hour after application.

Contraindications, side effects and overdose

For the safe and proper use of this antihypertensive drug, the patient should familiarize himself with the list of contraindications in which the use of tablets is completely prohibited. The absolute restrictions include the following:

  1. An individual reaction of the immune system to the component composition of the drug, which manifests itself in the form of an allergic reaction.
  2. Postponed allergic Quincke's edema.
  3. Negative reaction of the body caused by lactose intolerance.
  4. The age of the patient is up to 18 years.
  5. The period of pregnancy and lactation.
  6. Porphyrin disorder.

As well, the medication should be taken with caution in case of functional disorders in the work of the kidneys, heart defects, chronic disorders, diabetes mellitus. Given the possibility of a sharp decrease in blood pressure, enalapril is prescribed to patients under the supervision of a specialist if they have coronary disease, bilateral narrowing of the arterial wall, one preserved kidney, and a pathological violation of the cerebral organs of the brain.

Long-term use of the drug may be accompanied by the development of the following adverse reactions: fatigue, low blood pressure, collapse, pain in the heart, blood clots, sleep disturbance, allergies, anemia, and dry coughing attacks.

An overdose is signaled by such signs: a drop in blood pressure, a heart attack, seizures. In such cases, the patient needs to stop using the medication, and also contact a medical institution for an examination.

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