You can answer the question: Biseptolum is an antibiotic or not, if you look at the classification of antimicrobial drugs used in the treatment of diseases caused by pathogenic simple microorganisms.
Material Content:
Is Biseptol an antibiotic
Chemotherapeutic drugs are a large group of antimicrobial agents that suppress infectious processes in the human body. It consists of antibiotics, sulfonamides, nitrofurans, hydroxyquinolines, imidazole compounds, antifungal, antiviral and other drugs.
Antibiotics are the largest group of drugs classified by chemical composition, mechanism and spectrum of action. They are able to kill pathogenic microorganisms due to the destructive effect at the cellular level.
Biseptol is a combined antimicrobial agent consisting of two active substances - sulfamethoxazole from the sulfonamide group and trimethoprim - an antibiotic of synthetic origin from the diaminopyrimidine group. They have a bacteriostatic effect, which blocks the energy and metabolic processes in cells, which leads to a halt in the growth and death of bacteria.
The bactericidal properties of antibiotics make it possible to get a quick recovery from a bacterial infection. Bacteriostatic drugs require a longer medication.They are prescribed in the treatment of diseases occurring in mild or chronic forms.
Biseptol is an antimicrobial medication with a wide range of effects, not related to antibiotics.
Release forms and composition
Biseptol consists of 5 parts of sulfamethoxazole and 1 part of trimethoprim.
The drug is produced in tablet form in the form of a suspension (for children) and in ampoules (for intravenous drip):
- Biseptol 480 mg tablets contain 400 mg sulfamethoxazole and 80 mg trimethoprim;
- children's tablets with a total concentration of 120 mg consist of 100 and 20 mg of the active components of the drug (respectively);
- 5ml infant suspension contains a total dose of 240 mg;
- the main solution for dilution to a working solution and the procedure for intravenous infusion through a dropper is released in 5 ml glass ampoules with a concentration of 480 mg.
What the medicine helps
Biseptol productively acts in the treatment of infectious and inflammatory ailments caused by pathogenic microorganisms that are sensitive to the drug.
The medication helps to cure ailments:
- ear, throat and nose, upper and lower respiratory tract;
- liver, stomach, pancreas, intestines;
- genitourinary system;
- arising as complications after surgery or as a result of injuries and injuries.
Instructions for use and dosage
The brochure consists of general recommendations. Tablets are taken before or after a meal with plenty of water.
Biseptol is prescribed inside:
- adults and children over 12 years old for 2 tablets. (480 mg) 2 p. / Day., In case of severe infection - 3 tablets;
- with pneumonia, the dose is calculated according to the weight of the patient at the rate of 100 mg per 1 kg of weight, taken 4 times;
- with gonorrhea, 2 g for sulfomethoxazole 2 times;
- for chronic diseases - 1 table. 2 times;
- children 2-5 years old - 2 tablets (120 mg) 2 times; 5-12 years - 4 tablets.
The timing of treatment depends on the severity of the disease. The treatment lasts from 5 days to 2 weeks. In chronic infectious diseases, treatment may take a longer period of time. Treatment of acute brucellosis is 4 weeks.
In severe diseases, the drug is prescribed in the form of intravenous infusions using droppers:
- adults and children over 12 years of age, the solution is prepared with a concentration of 960 mg per working solution;
- children 6-12 years old are bred with 480 mg;
- children from 3-6 years old - 240 mg;
- in special cases, it is allowed to increase the concentration of the drug by 50% for all ages.
The procedure is carried out at intervals of 12 hours.
For children 6-12 years old, the dose of drugs is calculated by weight at 15 mg per 1 kg. To prepare the working solution, 5% or 10% glucose solutions, 0.9% physiological saline, Ringer's solution, 0.45% sodium chloride solution with 2.5% glucose solution are used.
You can not mix Biseptol with other drugs, except for the above solutions, since it is a combined preparation consisting of 2 components.
The duration of the procedure should be from 30 minutes to 1 hour and should not exceed 1 hour 30 minutes.
The activity of the effect of the drug on the body requires careful observation in the treatment of patients with folic acid deficiency, with manifestations of allergic reactions noted in the history of the disease, with bronchial asthma, abnormalities in the liver, kidneys, and thyroid gland.
Folic acid is prescribed for older patients to normalize hemoglobin levels.
With the appearance of edema associated with impaired renal function, the dose of the drug is reduced, and the intake intervals are increased. If, according to the results of the analyzes, the content of sulfamethoxazole in the blood reaches 150 μg / ml, the treatment is stopped and resumed when the concentration decreases to 120 μg / ml. Blood is taken for analysis several times a week as prescribed by a doctor in order to monitor the work of the liver and kidneys.
During pregnancy and lactation
Biseptol is not used at all stages of pregnancy. When breast-feeding a child, they are transferred to artificial feeding.
Drug interaction
Biseptol is very active when interacting with other medicinal substances, which can cause undesirable consequences, therefore it is not indicated simultaneously with salicylates, naproxen, PABA derivatives, thiazide diuretics, phenylbutazone, oral hypoglycemic drugs, phenytoin, and indirect anticoagulants.
Contraindications, side effects and overdose
The activity of any drug is always manifested not only in a positive way. Biseptolum can cause nausea, vomiting, diarrhea, dizziness in a sick person with weakened immune systems. Rashes on the skin are possible, accompanied by itching, and which can also provoke Quincke's edema.
Long-term use of the drug leads to a deterioration in blood composition - a decrease in neutrophils, platelets, white blood cells.
Contraindications for taking the drug are hypersensitivity to sulfonamides, liver, kidney, pregnancy, early life of the baby. For young and premature babies, Biseptol is used in inpatient therapy.
Symptoms of an overdose are observed in the form of a deterioration in general condition, nausea, vomiting, dizziness, and visual impairment.
Analogues of the combined drug
There are a large number of drugs with an identical combination of components, but produced under a different name in different countries. Instructions for use and dosage in the treatment of diseases have similar indications.
A lot of drugs are produced in Russia: Co - trimoxazole, Co - trimaxazole - Acre, Co - trimoxazole - Sti, Dvaseptol, Metosulfabol (available in the form of solutions for droppers).
Similar foreign drugs: Bactrim (France), Groseptol (Poland), Biseptol - 480 (Poland for intravenous administration), Be - Septin (Netherlands).
