Dysbacteriosis that occurs against a background of various factors is a serious disease that brings a number of inconveniences, in particular, stool disorders, increased gas formation and deterioration of the quality of the skin. The appointment of Acipol in this case is a proven and reliable means to eliminate both the symptoms of the disease and its underlying causes.

Description of the release form and composition

Acipol is available in two versions: Acipol capsules for adults and an oil solution intended for use by children.

The composition of one capsule includes active substances:

  • lactobacilli - their content is at least 107 CFU;
  • kefir polysaccharides from 0.3 mg per dose.

In addition, the composition includes excipients:

  • titanium dioxide - used in small quantities to give white color to the drug; It is a substance that is chemically pure and therefore safe for humans;
  • red iron oxide - due to its alkali resistance property, it is used as protection against the aggressive environment of the esophagus; when absorbed after natural dissolution, it is safe for the body;
  • gelatin is a link that helps form a capsule.

The package contains one, two or three blisters of 10 capsules in each.

A serving (five drops = 0.25 ml) of Acipol oil solution includes:

  • live lactobacilli - not less than 109 CFU;
  • bifidobacteria - not less than 5 * 108 CFU;
  • silicon dioxide - non-toxic filler;
  • DL-alpha tocopherol acetate is the main antioxidant of the human body, which contains vitamin E.

Sunflower oil is also used as a filler in the solution. The drug can be sold in the form of a therapeutic composition in a bottle with a dropper or in the form of an active substance (5 or 10 sachets) and a filler (in a dosage of 5 ml or 10 ml) for its dissolution. The release form does not affect the biological activity or effectiveness of the active substances.

Pharmacological action, pharmacodynamics and pharmacokinetics

The pharmacological action is based on the content of beneficial lactobacilli and fungi in the preparation. With their help intestinal microflora is normalized and its normal functioning is ensured.

The pharmacodynamics of Acipol is the delivery of lactobacilli and lactic acid fungi ready for action to the body. The lactobacilli contained in the medicine are one of the most important groups of bacteria that convert carbohydrates to lactic acid under conditions of a reduced amount of oxygen in the intestinal environment. This allows them to multiply even in the presence of pathogenic and conditionally pathogenic organisms. Lactobacilli create an acidic environment that allows you to successfully deal with microorganisms of this kind.

Kefir polysaccharides help produce high molecular weight carbohydrates with sugar breakdown residues, which increases the protective function of each individual cell. They serve as a reservoir that protects against drying, allows you to respond in a timely manner to critical situations and the reproduction of pathogenic organisms.

The pharmacokinetics of the drug Acipol cannot be considered as a separate process due to the content of such substances in the usual environment of intestinal microflora. As a result of the delivery of a probiotic to the body, the process of natural reproduction of lactic acid bacteria begins to accelerate, which positively affects the general condition of a person.

What helps Acipol

Probiotic Acipol is prescribed by a doctor if the balance of lactic acid bacteria is disturbed, which leads to the occurrence of conditions such as allergic inflammation of the skin, dysbiosis, redness of the mucous membranes.

The medicine helps with the following conditions:

  • acute infectious intestinal diseases provoked by bacteria of the species Shigella, Salmonella, Rotavirus;
  • colitis of various etiologies, including chronic, with simultaneous damage to the colon and small intestine, infectious and non-infectious in nature;
  • long-term treatment with drugs that violate the process of reproduction of lactobacilli, most often antibacterial;
  • diseases of the upper and lower respiratory tract of a constantly repeating or protracted nature;
  • allergic reactions of various manifestations, including chronic congenital pathologies of the skin.

Acipol is also successfully used for preventive effects on the body. With its help, it is possible to increase the resistance to pathogenic organisms of microflora and other infections.

Instructions for use and dosage for adults and children

Acipol for adults is prescribed:

  • for preventive measures against the possible occurrence of dysbiosis - 1 capsule during the day, treatment lasts no more than two weeks. Repetition is possible no earlier than four weeks after the end of the previous course;
  • in acute intestinal infections - 3-4 capsules per day, one at a time, the course of treatment is from 5 to 8 days;
  • when using antibiotic drugs and in other cases, the duration of treatment and the daily dose of the drug is determined by a specialist depending on the nature of the course of the disease.

Capsules should be taken as a whole half an hour before a meal, drinking plenty of water.

Depending on the age of the child and the severity of the disease, Acipol children are prescribed:

  • younger than three years old - the contents of one capsule are mixed in boiled water at room temperature or in breast milk. It is consumed within half an hour after dissolution along with food, two to three doses are shown per day;
  • older than three years - the scheme coincides with the appointment for adults.

The course of treatment is determined by the pediatrician. In the case of other forms of release, the method of administration and dosage is specified by the attending physician. Acipol is not recommended for children younger than three months of age.

During pregnancy and lactation

According to the instructions for use, Acipol can be taken both during pregnancy and during breastfeeding. Due to its natural components, Acipol is completely absorbed by the intestinal mucosa and does not cumulate in breast milk or amniotic fluid.

Alcohol compatibility

Studies on the compatibility of Acipol with alcohol have not been conducted. The nature of the interaction of the probiotic with alkaloids is also unknown.

Drug interaction

Acipol in its composition does not contain components that can in any way affect the action of the active substances of other drugs. Concomitant use with antibiotic drugs reduces the risk of dysbiosis. However, this manifestation occurs due to the delivery of additional biologically active components, and not because of the suppression of antibiotic-initiated actions.

Contraindications, side effects and overdose

The only contraindication for taking Acipol is the individual intolerance to any element of the drug. However, such clinical cases are extremely rare in practice.

No side effects were found, since the contained substances are symbiotic with respect to the human body and its microflora.

In addition, the probiotic is tolerated by patients without any consequences, and an overdose does not occur even when normal consumption is exceeded.

Probiotic Analogs

There are drugs whose mechanism of operation is similar to the action of the medication considered. The most popular Acipol analogues are represented by the following drugs.

Linex

Available in two forms: capsules or sachets for children.

It contains enterococci that appear in the intestinal microflora from the first days of life. This allows Linex to be prescribed from birth, which is an advantage in relation to Acipol.

However, the content of active ingredients in the medicine is lower, therefore, two capsules are required at a time. The cost of a similar course is twice as high compared to the presented tool.

Bifiform

The Acipol analogue is available in various formats:

  1. capsules - from two years;
  2. drops - from the first day of life;
  3. powder - from a year old;
  4. chewing tablets - from three years.

Moreover, the last two forms still contain B vitamins, which has an additional positive effect on the body.

In the components of the capsule there are no lactobacilli, only enterococci and bacteria of kefir fungi are present. In powder form and chewable tablets, there are no enterococci. And in the drops you can find lactobacilli and streptococci. Therefore, when prescribing a medicine, one should not agree to another form of release, except as prescribed by the doctor, since the necessary bacteria may not be present in the composition.

The course of treatment will cost the same cost as when using Acipol.

Lactobacterin

Available in one form - powder for solution preparation. The vial contains 5 doses for oral or topical use.

Only lactobacilli are present in the drug substance. A feature of the application is the possibility of use in gynecology.

Due to the specific form of release, it has a shorter shelf life compared to similar drugs. The cost of the course is twice as high.

The appointment of Acipol to normalize microflora and as maintenance therapy for intestinal disorders is justified.

The drug has proven effective when taken in all groups of patients both in the laboratory and in many years of practice.

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