A long course of aspirin is prescribed with a tendency to thrombosis to restore normal blood flow and prevent heart and vascular diseases. Errors in taking the drug provoke serious side effects. Before starting the course, carefully study how to take aspirin to thin the blood.

The composition of the drug

Aspirin is a household name and a synonym for the active ingredient, acetylsalicylic acid. Pharmacies sell traditional aspirin and the drug of the same name marked Cardio. Both drugs are part of the NSAID group, are available in the form of tablets with the same active substance. The difference lies in the concentration of acetylsalicylic acid and indications.

One tablet of traditional aspirin contains 0.5 g of the active ingredient. The medicine is used in acute conditions to relieve pain, reduce temperature, and inflammation. Aspirin Cardio tablets contain reduced doses of the active substance - 0.1 or 0.3 g, are coated to protect the stomach from the irritating effects of acid. This type of medicine is taken in a long course for the prevention of heart and vascular diseases.

How does Aspirin for blood thinning

The syndrome of increased blood viscosity develops with an increase in the number of blood cells relative to the volume of plasma.Such an imbalance leads to the aggregation of red blood cells, platelets, the formation of clots, slowing blood flow, impaired blood supply to tissues.

Aspirin is part of the drug group of antiplatelet agents. The active substance inhibits the production of thromboxane A2, inhibits the activity of platelets, deprives them of their ability to adhere and adhere to the walls of blood vessels. The patient's normal blood circulation is restored, the risk of developing thrombosis is reduced. Antiaggregant properties appear one hour after taking the tablets, persist for 1–2 days.

The medicine is prescribed in the following cases:

  • prevention of myocardial infarction in elderly patients with diabetes mellitus, obesity, high blood lipids;
  • angina pectoris - persistent or periodic pain behind the sternum;
  • violation of the blood supply to the brain, myocardium;
  • heart defects;
  • atrial fibrillation;
  • cerebral sclerosis, atherosclerosis;
  • severe hypertension;
  • predisposition to varicose veins, thrombophlebitis, endarteritis;
  • prevention of thrombosis after myocardial infarction, ischemic stroke, surgical interventions on the heart, blood vessels.

The medicine is prescribed for an excessively high level of blood coagulation, confirmed by laboratory tests.

Instructions for use and dosage

For preventive purposes, take 75-100 mg of acetylsalicylic acid once a day.

With this dose, side effects are reduced, but it is enough to inactivate platelets. The attending physician can increase the dosage of aspirin to 200-300 mg after examining the patient and obtaining test results.

The medicine increases the acidity of the stomach, therefore, during the reception, the recommendations are followed:

  • tablets are taken daily half an hour after a meal in order to protect the gastric mucosa;
  • the medicine is washed down with a cup of water or milk - it neutralizes the acidic environment, fruit drinks and juices are not used;
  • tablets with a protective shell are swallowed without chewing;
  • the drug is taken in the evening: at night a person does not move, the risk of thrombosis increases;
  • in case of accidental skipping, the reception is resumed without increasing the daily dose;
  • during the prophylactic or treatment course, alcohol is completely excluded; when taken together with ethanol, the risk of damage to internal organs and gastric bleeding sharply increases.

With a sudden attack of myocardial infarction, the drug becomes an emergency tool, reduces the risk of adverse effects. The duration of the course is determined by the attending physician.

During pregnancy and lactation

In the first trimester, aspirin is completely excluded, it provokes a miscarriage, abnormalities in the development of the fetus. At 4-6 months, the medicine is prescribed in rare cases in a low dosage. In the 3rd trimester, the drug again falls under the ban. Salicylates reduce muscle tone, blood clotting, so childbirth is accompanied by complications, heavy bleeding. The child may have malfunctioning kidneys, liver, pulmonary hypertension.

During lactation, you can not drink aspirin: the active substance is passed through breast milk to the baby, and the drug is prohibited until 15 years of age. If a nursing mother is prescribed a medication for health reasons, then the child is transferred to adapted mixtures.

Drug interaction

Aspirin enhances the effect of the following drugs:

  • coagulants;
  • thrombolytics;
  • antiplatelet agents;
  • methotrexate;
  • analgesics;
  • NSAIDs
  • digoxin;
  • valproic acid;
  • hypoglycemic agents.

With joint administration, the risk of damage to the gastric mucosa, bleeding, and impaired renal function due to the toxic effect of drugs increases. At the same time, Aspirin weakens the effect of diuretics, uricosuric agents. Glucocorticosteroids remove salicylates and reduce their therapeutic effect.

Contraindications, side effects and overdose

The medicine is not prescribed for patients with the following disorders:

  • bronchial asthma;
  • predisposition to hemorrhages - hemorrhagic diathesis;
  • severe kidney, liver, heart failure;
  • ulcers, gastrointestinal erosion, internal bleeding;
  • drug allergy to salicylates, NSAIDs, analgesics;
  • age up to 15 years: the drug provokes acute liver failure.

Aspirin changes the blood structure, reduces coagulation, so it is no longer taken 3-4 days before surgery, visiting a dentist, before giving blood for analysis.

The medicine inhibits the secretion of prostaglandins - protective hormone-like enzymes of tissues and organs, so after a long intake, side effects often develop:

  • Digestive tract disorders: nausea, heartburn, less often ulceration of the mucous membrane and bleeding of the gastrointestinal tract, bleeding gums.
  • Complications of the circulatory system: nosebleeds, hematomas, articular hemorrhages, anemia, hemorrhagic rashes.
  • Neurological disorders: dizziness, headache, hearing impairment.
  • Allergic reaction: itching, redness of the skin, rash, swelling of the mucous membranes, anaphylactic shock.
  • Respiratory system disorders: bronchospasm, nasal congestion.

Overdose occurs with the use of more than 100 mg per 1 kg of weight per day and is manifested by acidosis of varying severity. With a slight excess, nausea, vomiting, rapid breathing, tachycardia, headache, increased sweating occur. Severe cases are accompanied by confusion, pulmonary edema, impaired renal function, a sharp drop in pressure and acute heart failure until the heart stops. To avoid death, the patient is urgently washed in the stomach and called an ambulance.

Analogs of tablets

Based on acetylsalicylic acid release:

  • CardiASK;
  • Cardiomagnyl;
  • Aspicore
  • Thrombotic ACC;
  • Aspecard
  • Magnikor.

The listed drugs contain a reduced amount of active substance, are prescribed for the prevention of thrombosis. With the risk of developing cardiovascular diseases, the use of aspirin exceeds the possible risks. For healthy people without cardiological disorders, the medicine is not recommended.

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